About 80% of cancer patients need chemotherapy, and nausea, and vomiting are the most common gastrointestinal side effects in the chemotherapy, often in some patients difficult to accept the expected treatment, and even a fear, thus affecting the efficacy. Of chemotherapy-induced vomiting is a very complex process of pathological reflex, and the vomiting center of the medulla oblongata and the District of chemosensory stimulation by the anti-cancer drug metabolites.
In general, chemotherapy drugs, the incidence of vomiting caused by varying degrees. Vomiting rate of single-agent cisplatin, vomiting and a higher rate of cyclophosphamide, doxorubicin and other emetogenic effect is relatively weak with methotrexate, vincristine.
Select the appropriate anti-spit means necessary. First of all, should be based on age, gender, initial treatment or retreatment, individual status, patients with vomiting risk assessment, choose the means of prevention as early as possible, to help patients maintain a good mood, to avoid self-suggestion, and actively cooperate with treatment. Secondly, should be reasonable, effective use of antiemetic drugs, such as metoclopramide, dexamethasone, conventional pretreatment before chemotherapy.