The researchers published an article in the British Journal of Cancer "(British Journal of Cancer), said that the future risk for gallstones hospitalized patients the risk of fatal bile duct tumors is higher than the general population, but gallstone surgery to remove the The risk will come down gradually to normal levels. The bile ducts connect the liver, gallbladder and small intestine of the pipeline, cholangiocarcinoma refers bile duct cancer. Over the past decade, liver, endogenous tumor cases increased by nearly three times.
The study is based on Swedish national case database, tracking analysis from 1965 to 2008, 192,960 hospitalized gallstones patients and 345,251 received a cholecystectomy or gallstone removal surgery patients. About two-thirds of the patients were female.
Tracking within 6.4 years, 241 cases of gallstone patients suffering from cholangiocarcinoma; received cholecystectomy in patients with 325 cases of cholangiocarcinoma cases in 12 years. Patients in both groups, 30% of bile duct cancer occur within the liver, 70% occurred outside of the liver.
The study found that compared with the general population, patients with gallstones to suffer from two types of cancer risks are higher, of which men was three times higher for women is 2.5 times higher, and this high-risk still exists for 10 years.
Cholecystectomy patients, the risk of cancer than the general population about 38%, but this risk will come down gradually in the decades after. The researchers, gallstones may lead to chronic inflammation, chronic inflammation is an incentive trigger malignant tumors.
Warning: The researchers noted that many gallstones in patients with no explicit symptoms of the patients in this study may belong to a class of people of gallstone disease is more serious, and therefore also difficult to identify whether the study of patients with gallstones is universal.
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