Advanced Lung Cancer Treatment Targets And Drug Therapy

Therapeutic targets and drug therapy of advanced lung cancer
After through discussion, each department's doctors on the treatment of a disease, an opportunity to learn, and later met this patient, there will be a more reasonable treatment and sequencing. We talked about earlier in locally advanced. Next we look at the late stage patients. For patients with advanced medical treatment is the main method. Professor Zhang to tell us about, what is the late stage of lung cancer patients, drug treatment what progress?

Tension: Advanced lung cancer is the most encountered in our clinical lung cancer, symptoms of discomfort because of the lack of early stage lung cancer, newly diagnosed advanced lung cancer accounted for 85% of all lung cancer patients, the recent increase in popularity of healthy rate of early diagnosis, out-patients in late accounted for 70%, so with advanced lung cancer patients in the majority.

The Zhi Xiuyi: No clinical symptoms of early stage lung cancer, especially peripheral lung cancer. So once the clinical symptoms, including hoarseness, difficulty breathing, nausea, vomiting, pathologic fractures, are the typical symptoms of advanced lung cancer. Would like to add that yes, must attach importance to the timely detection of early lung cancer. Smokers smoked more than 20 or 30 years old, lung cancer and high incidence of the people of the region, the elderly over the age of 55 a year to do a healthy, especially for these high-risk groups of lung cancer, it must be done chest spiral CT.

Tension: As early as in about 4-5 years ago, the United States 100 years of lung cancer concluded clear ordinary chest X-ray can not be early detection of lung cancer. 2011 respiratory ten progress is the low-dose CT screening can reduce lung cancer mortality rate of 20%, it is proposed that we must pay attention to physical examination of the lung cancer screening in the future that, if the spiral CT, normal CT accuracy will be higher, but the sensitivity a bit weaker than the low-dose CT. Future screening for lung cancer using CT, chest X-ray.

Very large number of advanced lung cancer patients with advanced lung cancer is 4 of lung cancer from a professional perspective. In patients with advanced lung cancer treatment drug treatment, progress in the field of drug treatment.

The first emphasis on the concept of a treatment and the treatment of advanced lung cancer in particular reflect the importance of comprehensive treatment. Worthy of particular note is a look at several special advanced lung cancer: pulmonary lesions is controllable can be cut to distant metastasis, such as intracranial unilateral adrenal glands, contralateral lung of single metastases. The principle is to have surgery or radiology to work together to solve problems, the two parts respectively surgery surgical treatment, after systemic treatment. On the transfer of the adrenal gland, adrenal benign tumor is very large, requiring surgery in pathological puncture confirmed the transfer to go. In this case, for terminally ill people can still reach the target part of the cure. If the patient can not accept surgical treatment, radiotherapy or local radiofrequency ablation.

The progress of the cancer medication is relatively more prominent, of which the most progress is the molecular targeted therapy, which targeted more in-depth than the physical targeting of radiofrequency ablation or tumor targeting of certain chemotherapy drugs to the level of DNA. Non-small cell lung cancer is the fastest growing epidermal growth factor receptor tyrosine kinase inhibitor imatinib such drugs, such as Exeter, but patients using these drugs is best for the detection of molecular targets, so that patient the maximum benefit. Clinically, there are many drugs currently in clinical trials, will soon also apply to clinical, to make our patients more treatment opportunities, for more long-term survival, and to pay a smaller physical expenditure.

In addition, terminally ill patients to see a doctor, there is a big trick is to to pay attention to the clinical trials of new drugs.

Wang Green: To spread an idea, clinical studies are now the best way for this. Or there may be a better way to study. Clinical research is not done casually, one is its scientific nature, this method may be even better than the traditional methods now used, there is not harm the interests of the subjects.

Unlike some radical ideas that the patient as a small mouse. Clinical research, there are strict regulatory requirements to ensure its security. The majority of patients should be encouraged to co-ordination and participation in clinical research, Project Leader for specific patients for participation in clinical research, clinical research, according to circumstances. Why is the U.S. drug discovery and development of medical technology is so fast? Large medical institutions, research hospitals, a large proportion of patients are involved in this clinical study.

The Zhi Xiuyi: The treatment of advanced lung cancer, in addition to emphasizing its therapeutic effect, more emphasis on the patient's quality of life. Listed in recent years, these new molecular targeted drugs, such as Exeter imatinib, a good therapeutic effect in patients with advanced lung cancer at the same time, give a good quality of life of cancer patients treated decent dignity, but also the normal work and life. Here, I appeal to the relevant government departments, the face of so many patients with advanced lung cancer, with lung cancer diagnosis and treatment of new technologies, access to new drugs and clinical applications, on the one hand, to strengthen management, standardize the clinical diagnosis and treatment behavior, on the other hand is the perfect health insurance policy as soon as possible, so that the clinical efficacy, good quality of life of patients and new drugs into the Medicare reimbursement catalog, do not let those with advanced lung cancer patients impoverishment or back into poverty due to illness, it is recommended that the health care sector at all levels to increase in patients with advanced The concern of the lung cancer population.

Liu Baodong: Advanced lung cancer is multidisciplinary treatment for CT-guided radiofrequency ablation, it first has a direct damage to the tumor, a direct result of the primary tumor coagulation necrosis; radiofrequency ablation in local tumor formation vaccine trigger anti-tumor immune effect. Observation of the need for advanced lung cancer patients done radiofrequency ablation period of time, significant improvement in the quality of life, generally in good shape, life can take care of themselves. Another radiofrequency ablation Another role is to reduce the role of tumor burden, to lay a good foundation for adjuvant chemotherapy or supporting targeted therapy. Here to tell you, in Beijing, Xuanwu Hospital of lung cancer center radiofrequency ablation has entered the Beijing Medicare reimbursement directory.

Tension: As a doctor should be patient, the family members together to establish the concept of one kind with survival. Do not say we are introducing today so much progress and new drugs, they think of lung cancer, all-conquering, invincible. With survival is a very important concept, otherwise there will be two bad attitude or ruthless, or loss of confidence. In the case of peaceful coexistence of the patient and tumor, our treatment is effective. The future with the development of medical treatment of lung cancer and other benign diseases, like eat a medicine, the disease will be able to control.

Because of lung cancer or a tumor, he is a genetic disease, is the exception of a signal transduction pathway, it has been able to set down. Signals, the stop signal, not the future there will be a big breakthrough? Day, we do not know, is this day.